Here's a few places to stop and rest on I 81 in VA.
On up N on I 81 in Wytheville, VA stop at Smokey's BBQ at Exit 70 or 73. Peking Chinese Restaurant is outstanding also. C J's
Pizza is good if you have kids.
Smokey's BBQ @ 1090 East Main Street, Wytheville, VA 276 - 228 - 9014. http://smokeysbbq.com/
Peking Chinese Restaurant @ 105 Malin Drive, Wytheville, VA 276 - 228 - 5515. http://www.pekingva.com/C J's
Pizza @ 1025 West Lee Highway, Wytheville, VA 276 - 228 - 8448.
In Fairlawn @ Exit 105 is Troy's Steaks and Pizza but it's 10 minutes or so W of I 81 and W of Radford in Fairlawn in town. Good place for road food.
Troy's Steaks, Subs and Pizza @ 7339 Peppers Ferry Boulevard, Fairlawn, VA 540 - 731 - 4611.
In Christiansburg just on up the road a piece is Dude's, Due South, Farm House
and Summit. All are very good places to eat.
Dude's Drive In
@ 1505 Roanoke St., Christiansburg, VA 540 - 382 - 7901.
Due South BBQ @1465 Roanoke St., Christiansburg, VA 540 - 381 - 2922. http://www.duesouthbbq.com/Farm House
Food @ 285 Ridinger St., Christiansburg, VA 540 - 382 - 4253. .http://www.thefarmhouseonline.com/
Summit Restaurant @ 95 College St., Christiansburg, VA 540 - 382 - 7218. http://www.summitrestaurant.us/
Roanoke has quite a few nice restaurants but they are mostly in town. The restaurants near I 81 don't compare. If you should spend the night in Roanoke go check out these places for good road food. Blues BBQ, Fork in the Alley for pizza, burgers, sandwiches, Harbor Inn Seafood, Hollywood's Restaurant and Bakery for lunch/dinner, The Roanoker for breakfast and Wildwood Smokehouse BBQ.
Blues BBQ @ 107 Market Street SE, Roanoke, VA 540 - 344 - 5683. http://bluesbbqco.com/
Fork in the Alley @ 2123 Crystal Spring Ave. SW, Roanoke, VA 540 - 982 - 3675. http://forkinthealley.com/
Harbor Inn Seafood @ 7416 Williamson Rd., Roanoke, VA 540 - 563 - 0001.
Hollywood's Restaurant and Bakery @ 7770 Williamson Rd., Roanoke, VA 540 - 362 - 1812. http://www.hollywoodsrest...s_Website/Welcome.html
The Roanoker Restaurant @ 2522 Colonial Avenue SW, Roanoke, VA 540 - 344 - 7746. http://www.theroanokerres...t.com/pages/index.html
Wildwood Smokehouse @ 2041 Electric Road, Roanoke, VA 540 - 989 - 2100. http://www.wildwoodsmokehouseva.com/
The best option on I 81 near Roanoke, VA if you are trying to make good road time is Three Little Pigs at Daleville at Exit 150 5 miles N of Roanoke, VA. It's located in a small shopping center less than two minutes off W side of I 81 and serves great BBQ. It also has a very nice outdoor seating area and the menu includes sandwiches and salads for those who don't want BBQ. They also serve cold adult beverages. The shopping center has some very nice stores in case you are in need of road supplies. There are nice hotels on both sides of I 81 and a nice big truck stop to refuel and pick up road supplies. Three Little Pigs is a much better choice. Check it out next time you go by.
Three Lil Pigs BBQ @ 120 Kingston Dr., Daleville, VA 540 - 966 - 0165. http://www.threelilpigsbbq.com/
Get off I 81 at Exit 150B and go E to Highway 11. Turn left and go N a couple of miles to Pomegrante Restaurant for outstanding seafood and steaks for dinner.
Pomegranate Restaurant @ 106 Stoney Battery Road, Troutville, VA 540 - 966 - 6052. http://www.pomegranateva.com/
Home Place is a great restaurant several miles W of I 81 W of Roanoke at Exit 141 serving outstanding country food, good fried chicken and deserts in an old home. Just E of Lexington at Exit 188AB Frank's for the Memorie's is a great place for good road food with great outdoor dining.
Home Place Restaurant @ 4968 Catawba Valley Dr., Catawba, VA 540 - 384 - 7252.
Frank's for the Memories BBQ @ 2117 Magnolia Ave., Buena Vista, VA 540 - 261 - 5553. http://www.franks4thememories.com/
Lexington, VA has a number of good restaurants like Bistro on Main for lunch/dinner, Macado's for sandwiches, Sheridan Livery Inn and Restaurant for lunch/dinner, The Palms for lunch/dinner and drinks and Soutern Inn for fine dining lunch/dinner. Lexington is the home of VMI and W&L U. It's a beautiful town a few minutes W of I 81 and worth a visit.
Bistro on Main @ 8 North Main St., Lexington, VA 540 - 464 - 4888. http://www.bistro-lexington.com/
Macado's @ 30 North Main St., Lexington, VA 540 - 464 - 8201. http://www.macados.net/
Sheridan Livery Inn & Restaurant @ 35 North Main St., Lexington, VA 540 - 464 - 1887.http://www.sheridanliveryinn.com/
The Palms Restaurant @ 101 West Nelson St., Lexington, VA 540 - 463 - 7911. http://www.thepalmslexington.com/
Southern Inn Restaurant @ 37 South Main St., Lexington, VA 540 - 463 - 3612. http://www.southerninn.com/
Staunton is just W of I 81 and a very nice town also. It's home to Mrs. Rowe's country food breakfast, lunch and dinner, Wright's Dairy Rite, Staunton Grocery for casual fine lunch/brunch/dinner and The Depot Grill.
Mrs. Rowe's Family Restaurant @ 74 Rowe Rd., Staunton, VA 540 - 886 - 1833. http://www.mrsrowes.com/
Wright's Dairy Rite @ 346 Greenville Ave., Staunton, VA 540 - 886 - 0435. I81/EXIT220. ***http://www.dairy-rite.com/
Staunton Grocery @ 105 West Beverley Street, Staunton, VA 540 - 886 - 6880. http://www.stauntongrocery.com/
The Depot Grill @ 42 Middlebrook Ave., Staunton, VA 540 - 885 - 7332. http://www.depotgrille.com/
Harrisonburg has quite a few fine restaurants convenient to I 81. There are BBQ Ranch, Calley's Restaurant and Brewing Co. for good BBQ also, Dave's Downtown Tavern for good food and drinks, Donna Rosa for good Mexican, Jess' Quick Lunch, Joshua Wilton House Inn and Restaurant, Little Grill for breakfast, Local Chop and Grill House for fine dining, Smoking Pig BBQ and Village Inn.
BBQ Ranch @ 3311 N Valley Pike, Harrisonburg, VA 540 - 434 - 3296.
Cally's Restaurant and Brewing Co. @ 41 A Court Square, Harrisonburg, VA 540 - 434 - 8777. http://www.callysbrewing.com/
Dave's Downtown Taverna @ 121 S. Main St., Harrisonburg, VA 540 - 564 - 1487.http://www.davestaverna.com/
Dona Rosa @ 43 Linda Lane, Harrisonburg, VA 540 - 442 - 7672.
Jess' Quick Lunch @ 22 S. Main St., Harrisonburg, VA 540 434 - 8282.
Joshua Wilton House @ 412 South Main St., Harrisonburg, VA 540 - 434 - 4464. http://joshuawilton.com/
Little Grill @ 621 North Main St., Harrisonburg, VA 540 - 434 - 3594. http://littlegrillcollective.com/
Local Chop and Grill House @ 56 West Gay St., Harrisonburg, VA 540 - 801 - 0505. http://www.localchops.com/
Smoking Pig @ 56 East Wolfe St., Harrisonburg, VA 540 - 433 - 3917. I81/EXIT247AB.
The Village Inn @ 4979 South Valley Pike - S Main St., Harrisonburg, VA 540 - 434 - 7355. http://www.thevillageinn.travel/
Just up I 81 a few miles is Southern Kitchen serving outstanding country food for breakfast, lunch and dinner at Exit 264.
Southern Kitchen @ 9576 South Congress St., New Market, VA 540 - 740 - 3514.
On past Strasburg at Stephens City is Butcher Block BBQ @ Exit 264.
Butcher Block BBQ @ 131 Town Run Lane, Stephens City, VA 540 - 869 - 4141. http://www.butcherblockbuffet.com/
The Naked Oyster is a great place for lunch/dinner at Winchester at Exit 31A.
Naked Oyster @ 2444 Valley Avenue, Winchester, VA 540 - 678 - 0778. http://www.thenakedoysterwinchester.com/