Astoria: Ships Inn+the column. you'll feel good if you start at the end of Lewis & clark's journey. Maritime museum and trolley.
tillamook: gotta' stop at the cheese factory.(see stern's review) 3 capes tour is beautiful and netarts bay is cool
Neskowin: Stop at THIS beach. Unlike most oregon beaches, this is wide sheltered by the mini-mountain you'll see. your kids can play in the creek that winds through the beach.
newport:most sophisticated city on the oregon coast. State aquarium http://www.oregonlive.com/sharks/cams/index.ssf/multi.ssf.
= the bay waterfront area, Mo's salt water taffy and a "ripley's believe it or not" for the kids.
Yachats:blue whale to eat and the best park access on the coast. turn at the grocery
store and 2 blocks to great ocean access where the yachats river enters the ocean.
next mountains and sea lions.
sand dunes then florence: an A&W is on the left complete with car hops.
I'd keep going through North bend/coos bay. Bandon,then on to Gold Beach which bears a stop to ride the jet boat up the rogue.
brookings is next and then it's California.
a hint: if you journey east to 199(about 10 miles) in between brookings/harbor and cresent city, one of the very best units of jedediah Smith State park , groves of redwoods in very peaceful settings. no postcard shops etc., just Wow!